Industry Outlook

The global antihistamines market will grow at a CAGR of 8.7% during the forecast period from 2018 to 2026. Antihistamines exemplify a class of drugs that block the histamine type-1 (H1) receptors. H1-receptors are extensively scattered and predominantly found on smooth muscle of the gastrointestinal tract, bronchi, uterus, and large blood vessels. The key applications of antihistamines are allergic rhinitis, conjunctivitis, urticaria, atopic dermatitis, anaphylaxis, and others. In year 2016 according to European Academy of Allergy and Clinical Immunology (EAACI), around 150 million or more Europeans suffer from chronic allergic conditions and further anticipated that by 2025 half of the total population of Europe will suffer with chronic allergic diseases. Thus, rising global prevalence of allergies expected to increase the demand for antihistamines in the near future.

Second-generation antihistamines expected to retain its market dominance during the forecast period

Second-generation antihistamines such as acrivastine, cetirizine, desloratadine, fexofenadine, levocetirizine, and loratadine are preferred as first-line of treatment in diseases such as allergic rhinitis, urticaria, and atopic dermatitis. The key factors assisting the growth of second-generation antihistamines are rising prevalence of allergies, increasing awareness related to early diagnosis & treatment of allergies, and overall development in the treatment technology. However, the main reason for prescribing second-generation antihistamines is there are very few second-generation antihistamines that cross blood-brain barrier and have sedating effect. Cetirizine causes drowsiness that may lead to accidents with people driving car or handling heavy machinery. Thus, levocetirizine is now preferred over cetirizine due to its non-sedating effect. Second-generation antihistamines possess a longer duration of action and plasma half-life compared to first generation drugs, which makes it easy to decrease the number of daily intakes.

Asia Pacific will exhibit double-digit growth during the forecast period due to increasing patient awareness related to allergic reactions

Asia Pacific observed as the fastest growing region in antihistamines market due to rising awareness in patients and medical practitioners related to allergic conditions, and developing digital healthcare infrastructure. According to World Allergy Organization (WAO), prevalence of allergic diseases is increasing globally, including in the Asia-Pacific region. The published report of WAO suggest that in 2016, 20% to 30% of the world’s population suffered from some or other form of allergic conditions. The market experts believe that physicians in Asia-Pacific have access to all available second-generation H1- antihistamines due to which they are able to follow international guideline recommendations for first-line treatment of allergic rhinitis and urticaria effectively. Thus, overall awareness related to early diagnosis and treatment of allergy conditions have assisted the growth of antihistamines in Asia Pacific region specifically in developing countries such as India & China.

Antihistamines in pipeline are on the verge of exploring several other applications

Antihistamines in phase III of clinical trials are exploring applications such as chronic spontaneous urticaria, angioedema, functional dyspepsia, hemodynamic instability, vasoplegic syndrome, elbow injury, and others. Thus, post approvals for these applications antihistamine market will grow exponentially during the forecast period from 2018 to 2026. The major companies equipped with antihistamines under pipeline are Novartis AG, Celgene Corporation, F. Hoffman-La Roche, Genzyme (Sanofi), Ache Laboratorios Farmaceuticos S.A., Merck & Co. Inc., and Faes Farma, S.A. Thus, strong pipeline expected to boost the overall growth of antihistamines market throughout the forecast period.

This report further describes the major qualitative assessment factors including key market trends, market drivers & restraints, to assist in better understanding of global antihistamines market. Furthermore, the key players are analyzed graphically based on their product offering, market strategies and business strength. The report also provides attractive investment proposition based on the extensive geographical research carried out based on PESTEL analysis. Key players profiled in the report include Bayer AG, Almirall S.A., Johnson & Johnson, AstraZeneca plc, Novartis AG, Pfizer, Inc., Sanofi SA, Boehringer Ingelheim GmbH, Merck & Co., Inc., Akorn, Inc., Teva Pharmaceutical Industries Ltd., and others.

Historical & Forecast Period

This study report represents analysis of each segment from 2022 to 2032 considering 2023 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2024 to 2032.

The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.

Research Methodology

The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Antihistamines market are as follows:

• Research and development budgets of manufacturers and government spending
• Revenues of key companies in the market segment
• Number of end users and consumption volume, price and value.
• Geographical revenues generate by countries considered in the report
• Micro and macro environment factors that are currently influencing the Antihistamines market and their expected impact during the forecast period.

Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.

Key questions answered in this report

• What are the key micro and macro environmental factors that are impacting the growth of Antihistamines market?
• What are the key investment pockets with respect to product segments and geographies currently and during the forecast period?
• Estimated forecast and market projections up to 2032.
• Which segment accounts for the fastest CAGR during the forecast period?
• Which market segment holds a larger market share and why?
• Are low and middle-income economies investing in the Antihistamines market?
• Which is the largest regional market for Antihistamines market?
• What are the market trends and dynamics in emerging markets such as Asia Pacific, Latin America, and Middle East & Africa?
• Which are the key trends driving Antihistamines market growth?
• Who are the key competitors and what are their key strategies to enhance their market presence in the Antihistamines market worldwide?