Hepatic Encephalopathy Therapeutics Market Is Projected to Expand At A CAGR Of 6.5% Between 2023 And 2031. As per the citing of the National Organization for Rare Diseases (NORD) 2016 report, hepatic encephalopathy is described as brain disorder in patients previously suffering with chronic liver ailments such as liver cirrhosis, hepatitis and acute liver failure. If effectively diagnosed, hepatic encephalopathy occurs in almost two-thirds of the patients suffering with liver cirrhosis. Hepatic encephalopathy is categorized into 3 types such as Type A (acute liver failure), Type B (portal systemic bypass without liver disease) and Type C (liver cirrhosis). The exact disease etiology is unknown but the disease is triggered by accumulation of toxins in the bloodstream as the diseased liver fails to neutralize the toxins. The clinical manifestation associated with hepatic encephalopathy are confusion, anxiety, lethargy, seizures, confused speech, personality changes and poor body movements. The key factors driving the hepatic encephalopathy therapeutics market are rising prevalence of liver disorders, lack of nutrients in daily food intake and increasing public health awareness resulting in early diagnosis and treatment.
The diagnosis of hepatic encephalopathy includes blood tests, liver function test, detection of serum ammonia levels, and an encephalogram of the brain to measure the electrical activity of the brain. There are numerous therapeutic approaches to manage the severity of hepatic encephalopathy, but the reduction of plasma ammonia is the most preferred strategy. Lactulose is the first line of treatment as it changes the acidity of the stool in order to reduce the production of ammonia by killing intestinal bacteria. Probiotics and thiamine are useful in the treatment of hepatic encephalopathy by increasing the expulsion of ammonia genic bacteria by causing the bowel to get fermented by colonic bacteria to produce lactic and acetic acid. In 2010 the USFDA approved Rifaximin for the treatment of hepatic encephalopathy by acting on the microorganisms in the intestinal tract producing ammonia.
Key players identified for the Hepatic Encephalopathy market include:
Mallinckrodt Pharmaceuticals, Salix Pharmaceuticals, GlaxoSmithKline plc., Pfizer Inc., ASKA Pharmaceutical Co., Ltd., Bausch Health, Johnson & Johnson Services, Inc., Janssen Global Services, Takeda Pharmaceutical Company Limited, Merck & Co., Inc. and others.
Historical & Forecast Period
This study report represents analysis of each segment from 2022 to 2032 considering 2023 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2024 to 2032.
The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.
Research Methodology
The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Hepatic Encephalopathy Therapeutics market are as follows:
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.
ATTRIBUTE | DETAILS |
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Research Period | 2022-2032 |
Base Year | 2023 |
Forecast Period | 2024-2032 |
Historical Year | 2022 |
Unit | USD Million |
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Region Segment (2022-2032; US$ Million)
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Key questions answered in this report