Epigenetics is a term referred to the study of long-term changes in gene expression, which may or may not be heritable, and do not involve the changes to the DNA sequence. It is estimated that epigenetics market will grow at a double digit CAGR over the forecast period from 2018 to 2026. Some major factors assisting the market growth are increasing awareness about epigenetics in different medical fields, growing funding for research and development activities and increasing prevalence of complex diseases such as cancer. Conversely, lack of widespread availability of skilled professionals and existence stringent regulatory framework governing the field of epigenetics and genetic research restrain the market growth. 

The global epigenetics market is classified on the basis of products, technologies and applications. Market estimation and forecast analysis for each of these classes for the period from 2016 to 2026 are included in this report study along with respective CAGRs during the forecast from 2018 to 2026. On the basis of product types, the epigenetics market is categorized as kits (ChiP-Seq Kits, whole-genome amplification kits, 5-HMC and 5-MC analysis kits and other epigenetics kits), reagent, enzymes (DNA-modifying enzymes, protein-modifying enzymes and RNA-modifying enzymes), instruments and bioinformatics tools. Based on applications, this market segmented as cancer, metabolic diseases, immune diseases, cardiovascular diseases and other applications. DNA methylation, histone modification and other techniques are the technologies studied in this report.

Alongside the numeric data (market size and forecast), subjective informational sets and assessment tools are also incorporated in this report to cover in-depth analysis of general market circumstance and future projections. Information such as epigenetics market drivers, challenges and opportunities cover insights related to current trends in the global epigenetics market. Attractive investment proposition, company profiles and market positioning of key manufacturers provide insights on the competitive situation of the global epigenetics market. This report also presents company profiles segment which features key data related to the prominent players involved in epigenetics market.

Epigenetics is the term referred to heritable changes in genetic modifications that do not involve changes in the primary DNA sequence; it plays important role in gene expression. Epigenetic changes are regular and naturally occurred however, several factors such as lifestyle, disease state, nutrition, age and environment etc. may lead to epigenetic changes. The global epigenetics market is expected to witness rewarding development over the forecast period owing to increasing importance of epigenetics to understand mechanisms of human development, aging and origins of different forms of diseases such as cancer, mental illness, heart disease and several others. Currently, the demand for kits is highest in market and will also undergo the fastest market growth over the forecast period primarily due to, continuous advancement in the nature and precision of kits, wide availability of robust, simple-to-use, and cost-efficient kits, and increasing adoption from research laboratories. Furthermore, enormous investments in R&D, increase in the prevalence of several life-threatening diseases and increased government funding for life science research are other factors propelling the growth of epigenetics kits market globally.

From the last few decades, the demand for epigenetics study in characterization of various diseases has increased in the field of drug discovery and life science research. Applicability of epigenetics study for complex diseases such as cancer, behavior plasticity, autoimmune diseases, neurodegenerative and psychological disorders, addiction etc. has considerably increased in the market. In 2017, cancer is the major revenue-generating segment in the global epigenetics market because the reported evidence that epigenetic modifications have a considerable effect on cancer development and therefore management. Non-oncology segment of epigenetics market comprises metabolic diseases, infectious diseases, cardiovascular diseases, and others. Metabolic diseases was the largest share holding sub-segment in the year 2014 at over 32.0% due to the high impact of high-fat diet on DNA modifications and epigenetic regulation of metabolism.

However, the cardiovascular disorders segment is expected to be the fastest growing segment over the forecast period owing to the emergence of technologies such as microRNA modifications in diagnosis and treatment of cardiovascular disorders. Other factors such as increase in prevalence of different forms of cancer, strong product pipeline and higher number of unmet needs are fueling the growth epigenetics in cancer.

Epigenetics is the study of modification in gene expression that does not involve changes to the genetic code. The epigenetics market will grow significantly over the forecast period owing to its robustness. Furthermore, increasing applicability of epigenetics in targeted therapy and personalized medicine would influence the market growth over the forecast period. DNA methylation, non-coding RNA associated gene silencing and histone modification play an essential role in initiating and sustaining epigenetic changes. The introduction of technological advancement such as Methylation Sensitive PCR (MSP) and rapid adoption of these products to improve diagnostics efficiency are some factors attributing for its largest share. It is observed that the demand for DNA methylation technique was the highest in market as it is a rapid and accurate technique for whole genome analysis. DNA methylation technique is used in the preparation of DNA for methylation analysis; it includes the selection of methylated DNA, enzymatic compartmentalization by methylation sensitive enzymes, and biochemical treatment of the DNA. DNA methylation technique has great potential in understanding the functional mechanisms in complex disease and personalized drug development. Moreover, methylation plays a fundamental role in cell divisions, differentiation, apoptosis, growth factor response, detoxification, metastasis etc. that have promoted huge advances in the early detection of cancer. 

North America is the current geographical leader in the worldwide epigenetics market. Some key factors such as increase in demand for personalized medicines coupled with greater awareness between both patients and caregivers play a vital role in the dominance of this region. North America also houses some of the largest pharmaceuticals manufacturers which are actively involved in research and development of development of novel drugs in oncology and non-oncology treatments. Furthermore, some other factors such as well-developed healthcare infrastructure, rapid rise in popularity of epigenetics, higher prevalence of complex diseases and early acceptance of advanced technologies are fueling the market growth in North America. On the other hand, evolving regulatory policies in key counties such as China and India, growing research and development outsourcing and increasing population of patients with chronic diseases have a supportive role in the high market growth rate in Asia Pacific. Collaborations between domestic life science companies and international pharmaceuticals companies for the development of better therapeutics also facilitate the growth of this region.

Historical & Forecast Period

This study report represents analysis of each segment from 2022 to 2032 considering 2023 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2024 to 2032.

The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.

Research Methodology

The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Epigenetics market are as follows:

• Research and development budgets of manufacturers and government spending
• Revenues of key companies in the market segment
• Number of end users and consumption volume, price and value.
• Geographical revenues generate by countries considered in the report
• Micro and macro environment factors that are currently influencing the Epigenetics market and their expected impact during the forecast period.

Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.

Key questions answered in this report

• What are the key micro and macro environmental factors that are impacting the growth of Epigenetics market?
• What are the key investment pockets with respect to product segments and geographies currently and during the forecast period?
• Estimated forecast and market projections up to 2032.
• Which segment accounts for the fastest CAGR during the forecast period?
• Which market segment holds a larger market share and why?
• Are low and middle-income economies investing in the Epigenetics market?
• Which is the largest regional market for Epigenetics market?
• What are the market trends and dynamics in emerging markets such as Asia Pacific, Latin America, and Middle East & Africa?
• Which are the key trends driving Epigenetics market growth?
• Who are the key competitors and what are their key strategies to enhance their market presence in the Epigenetics market worldwide?